This aspect of nutrition has produced mixed results over the years and is a question I get asked quite often. The answer is yes….to an extent.

I would point out it depends on what you are trying to achieve, if you are simply looking to lose weight (fat mass) what seems to be apparent is being in a calorie deficit, if however you are looking to maintain lean mass or build lean mass it may be slightly different.

The hypothesis is that increasing meals increases the thermic effect of food ultimately increasing total energy expenditure, however the science might tell us something different.

MEAL FREQUENCY ON FAT MASS

Research on meal frequency and fat mass presents mixed findings, with no clear consensus on whether eating more frequently leads to greater fat loss. A systematic review published in Nutrients found no significant relationship between meal frequency and body weight or fat mass when total caloric intake was controlled (Schoenfeld et al., 2015). Similarly, a meta-analysis in the Journal of the International Society of Sports Nutrition concluded that while some studies suggested a higher meal frequency might slightly reduce fat mass, these results were largely driven by a single study, making generalisability uncertain (Taylor & Garvey, 2014). Conversely, some evidence suggests that increased meal frequency may improve appetite control and reduce overeating, potentially aiding fat loss over time (Leidy & Campbell, 2011). However, the overall scientific consensus suggests that total energy balance—rather than the number of meals per day—is the primary driver of changes in fat mass.

Science supports this from a biological and physiological standpoint in that when energy intake exceeds energy expenditure, the surplus energy is then stored, when energy intake is less then energy expenditure, this results in loss of body mass. (Pang et al, 2014). This equation (energy balance) sits parallel with the foundations of thermodynamics, the second law, which theorises that energy is not destroyed, instead it postulates that energy transfers from one form to another. From this it is argued that the human body is an open system and that environmental, biological, and nutritional factors can influence the direction of energy expenditure and storage, when encompassing the second law of thermodynamics (Thomas et al, 2009).

MEAL FREQUENCY ON LEAN MASS

Recent research has explored the relationship between meal frequency and lean mass, yielding mixed results. A 2015 meta-analysis by Schoenfeld et al. found that increased meal frequency was associated with reductions in fat mass and body fat percentage, as well as an increase in fat-free mass. However, sensitivity analysis revealed that these positive effects were primarily driven by a single study, casting doubt on their generalisability. Similarly, a 2020 systematic review and network meta-analysis reported no significant impact of meal frequency on anthropometric outcomes, including lean mass, when total energy intake was held constant. Conversely, a 2015 study by Alencar et al. suggested that increased meal frequency might attenuate fat-free mass losses during a portion-controlled weight loss diet. Overall, these findings suggest that while meal frequency may have some influence, total protein intake and overall dietary quality are more critical factors in managing lean mass.

TAKE HOME

If you are looking to lose body fat the gold standard seems to remain as a calorie deficit, however if you ensure you have the correct NET protein intake you will preserve lean mass. In terms of lean mass maximising muscle protein synthesis and ensuring your NET protein intake is adequate seems to be more important than how many meals you eat.

REFERENCES

Canuto R, da Silva Garcez A, Kac G, de Lira PIC, Olinto MTA. Eating frequency and weight and body composition: a systematic review of observational studies. Public Health Nutrition. 2017;20(12):2079-2095. doi:10.1017/S1368980017000994.

Impact of Meal Frequency on Anthropometric Outcomes: A Systematic Review and Network Meta-Analysis of Randomized Controlled TrialsSchwingshackl, Lukas et al.Advances in Nutrition, Volume 11, Issue 5, 1108 – 1122.

Schoenfeld BJ, Aragon AA, Krieger JW. Effects of meal frequency on weight loss and body composition: a meta-analysis. Nutr Rev. 2015 Feb;73(2):69-82. doi: 10.1093/nutrit/nuu017. PMID: 26024494.

Blazey P, Habibi A, Hassen N, Friedman D, Khan KM, Ardern CL. The effects of eating frequency on changes in body composition and cardiometabolic health in adults: a systematic review with meta-analysis of randomized trials. Int J Behav Nutr Phys Act. 2023 Nov 14;20(1):133. doi: 10.1186/s12966-023-01532-z. PMID: 37964316; PMCID: PMC10647044.